Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
Lysinum
(S)-α,ε-diaminocaproic acid
6-ammonio-L-norleucine
Lysina
Lysine hydrochloride
L-lys
Lysine dihydrate
Lysine
(S)-2,6-diaminohexanoic acid
Lysine monohydrate
(S)-lysine
Lysine acid
L-Lysine
L-2,6-Diaminocaproic acid
LYS
Lysine acetate
L-Lysin
Brand Names
Aminosyn II
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Aminosyn II and Dextrose
Olimel 5.7%
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Aminosyn II with Electrolytes in Dextrose with Calcium
Clinimix E
Olimel 3.3% E
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn 7%
Nutrineal Pd4
Aminosyn
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Hepatasol
Aminosyn-PF 10%
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Olimel 7.6%
Aminosyn 8.5%
Smofkabiven Peripheral
Olimel 5.7% E
Primene 10%-liq IV
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Travasol
Aminosyn-PF 7%
Aminosyn 5%
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn II In Dextrose Injection
Perikabiven
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn Sulfite Free
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Aminosyn II 5% Inj
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Aminosyn II 8.5% With 50% Dextrose
Travasol Amino Acid Inj 8.5%
Smofkabiven Extra Nitrogen
Aminosyn HF
Kabiven
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Clinisol
Aminosyn RF Injection
ProcalAmine
Imubolic
Aminosyn 3.5% M
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Aminosyn II 8.5% Injection
Aminosyn II in Dextrose
Plenamine
Xyzmune
NephrAmine
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
FreAmine HBC
Aminosyn II 7% Injection
Novamine
Clinimix
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Smofkabiven Electrolyte Free
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Periolimel 2.5% E
Primene
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Aminosyn 10% W Electrolytes
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
FreAmine III
Olimel 7.6% E
Premasol - sulfite-free (Amino Acid)
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Olimel 4.4% E
Aminosyn-PF
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn RF
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
HepatAmine
Travasol Inj Without Electrolytes 5.5%
Aminosyn 8.5% Injection With Electrolytes
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Olimel 4.4%
Vamin N
Travasol E
ProSol
Effervescent Potassium Chloride
Primene 10%
Aminosyn II 10% With Electrolytes
Travasol Amino Acid Inj 5.5%
Smofkabiven
Nephramine Liq IV
TrophAmine
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Synthamin
Aminosyn II with Electrolytes
RenAmin
Aminosyn II 7% With 50% Dextrose
Essepna
Travasol Inj Without Electrolytes 8.5%
Lysakare
Aminosyn II 7% With 10% Dextrose
Vamin 18 Electrolyte-free
8.5% Freamine III
Renamin (amino Acids) Injection
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
20% Prosol
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
