Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
L-Lysine
L-Lysin
L-lys
(S)-lysine
(S)-2,6-diaminohexanoic acid
Lysine acetate
Lysine
6-ammonio-L-norleucine
Lysine hydrochloride
Lysina
Lysine dihydrate
Lysinum
LYS
Lysine acid
Lysine monohydrate
L-2,6-Diaminocaproic acid
(S)-α,ε-diaminocaproic acid
Brand Names
Aminosyn 3.5% M
Aminosyn II 8.5% With 50% Dextrose
8.5% Freamine III
Aminosyn 7%
Premasol - sulfite-free (Amino Acid)
Periolimel 2.5% E
Lysakare
Olimel 4.4% E
Vamin N
Olimel 3.3% E
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Aminosyn II 7% Injection
Aminosyn II 5% Inj
Aminosyn II with Electrolytes in Dextrose with Calcium
Aminosyn RF Injection
Smofkabiven Extra Nitrogen
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Perikabiven
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Clinisol
Aminosyn II 10% With Electrolytes
Aminosyn II in Dextrose
FreAmine HBC
Aminosyn II with Electrolytes
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn RF
Primene
Renamin (amino Acids) Injection
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Effervescent Potassium Chloride
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
20% Prosol
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
ProcalAmine
Primene 10%-liq IV
Imubolic
Aminosyn Sulfite Free
Vamin 18 Electrolyte-free
Aminosyn 5%
Plenamine
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Aminosyn 8.5% Injection With Electrolytes
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
RenAmin
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Aminosyn-PF 10%
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Aminosyn 8.5%
Kabiven
Travasol Inj Without Electrolytes 8.5%
Novamine
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Olimel 7.6%
Xyzmune
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
FreAmine III
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Smofkabiven Electrolyte Free
Travasol Amino Acid Inj 5.5%
Travasol
Aminosyn II In Dextrose Injection
Travasol E
Aminosyn 10% W Electrolytes
Clinimix
Aminosyn-PF
Olimel 7.6% E
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Olimel 4.4%
Clinimix E
Aminosyn II
Hepatasol
Olimel 5.7% E
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Essepna
Aminosyn II and Dextrose
TrophAmine
Nephramine Liq IV
Travasol Inj Without Electrolytes 5.5%
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Aminosyn-PF 7%
Aminosyn II 7% With 50% Dextrose
Aminosyn II 7% With 10% Dextrose
Travasol Amino Acid Inj 8.5%
Aminosyn II 8.5% Injection
Synthamin
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Nutrineal Pd4
Aminosyn HF
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
NephrAmine
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Smofkabiven Peripheral
Aminosyn
HepatAmine
Primene 10%
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
ProSol
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Olimel 5.7%
Smofkabiven
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682