VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152
Name	Thiamine
Groups	investigational vet_approved nutraceutical approved
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Thiamine Vitamin B1 Thiaminum thiamine(1+) ion Aneurin thiamine(1+) Thiamin Tiamina Thiamine mononitrate Antiberiberi factor Thiamine chloride thiaminium Thiamine hydrochloride
Brand Names	Multi Plex II - Tab Insur-all Vitamin Supplement B Complex W C and B12 Inj Chela-manganese 50 Plus Renate DHA Isotonix Multitech Vitamin Mineral Supplemen Ventrixyl Multi-vitamins With Minerals Multiple Vitamins - Tablet Nutrifer Plus Tablets Vitalife - Capsule Fizz Multivitamins for Kids W C Loz Zyvit B-100 Vitamin Supplement Childrens Chewable Multiple Vitamins W.iron Revitex Ampoules Et Comprimes Bal-Care DHA Essential Penta-thion Pwr Allbee With C 550 Cap Vp-heme Ob DHA CitraNatal Essence Prenatvite Bugs Bunny and Friends Multiple Vitamins Multinate DHA Extra Vitamin B Compound W Vit C 250mg Tab Mycelized Childrens Multi-vitamin Liq Stress B-complex Plus Iron With Vitamins C&e Beminal W C Fortis Inj M.V.I. Adult Multivitamine Supravite Pour Enfants Neonatal Vitamin Vege Swiss One Multivitamin W Chel Mins Tab Complete One-A-day - Tab Dexatrim Tablets Duet DHA 400 ec Paramettes Syrup Multi-Vit-Flor Stress Formula + Iron Mvc 9 Plus 3 Inj MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement 50 Plus Ultimate Tab Fortamines-10 Comprimes Spectrum 2 Cap B-50 Hi Potency B Vitamins Tab K.L. Vitamin-mineral Thiamine Hydrochloride Inj 100mg/ml USP Paramettes Multivits Plus Iron Tab (teens) PreferaOB plus DHA Super Vitalex Ampoule Buvable Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Dothelle DHA Right Choice A.M. Multi Formula - Caplet Balanced B-complex Vit + Vit C&e Tab B 50 Capsules Vitrexate Vol-Plus B-complex 50 Corvite Free Vitamin B1 Tab 100mg USP Daily Balance Tab 50 Plus Multiple Vitamins & Minerals One A Day Multiple Vit W Minerals Pregvit Folic 5 TL-Folate Folivane-OB Vitamin B + C Cap Vc II Megavite Rx B-Combo Multi Vitamin and Fluoride Multivitamin with Fluoride Multiple Vitamins Plus Iron Tab Multi-Vitamin Fluoride Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Bacmin Children's Chewable Multivitamins and Minerals Multi Flow Tablets B-plex 100 Multi-actin Davimet Orifer F Venexa VP-Vite Rx Escavite D Magnum-75 Vitamin and Mineral Supplement Essential Vitamins and Minerals Vitamine B1 Tab 100mg USP Children's Chewable Multi Vitamins With Iron Tablets PR Natal 430 ec Livron Plus Ampoule Thiamine HCl Tab 50mg Genicin Vita-Q Natal-V RX Multi-vitamin/Multi-mineral Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals PreQue 10 Hi Potency Balanced B-100 Complex - Tab Liqui B Complex Lorid Mini-B Tab Prenate Elite Vita-B Spectrum Performa Multivitamins and Minerals Tablets Vitaday Tab Multi-Nate 30 NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Rocky Mountain Multiple Vit and Min Mega Tab Fem Time Tab Stress Tab Multivitamin Drops with Fluoride V-Natal Balanced B-50 B-complex Vitamins Tab Multivitamins and Minerals Tablets Thrivite 19 Virt-Nate DHA Multivit Et Fer Ampoules Et Comprimes Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Tandem Plus Virt Vite GT Stress B With 1000 Mg Vitamin C Floravit - Syr Super Multi Somavit Brand Vitamins and Minerals Complex Multi Vitamin - Mineral P.N. Vitamin-mineral Drink Low Potency B Complex Tab Multi-11 Pregnancy Multivitamin Folic 5 Hemarexin Liquid and Drinkable Ampoules Maltlevol Liq Prenatal Vitamins Plus Low Iron Totalvit Plus Vital Be-100 Men's Biomultiple Vitamin and Mineral Supplement Complexe B Compose 75 Multi - N.T.O.x Formula - Tab Super Vita Vim Multivitamins and Minerals Childrens Chewable Multiple Vitamins Tab Pretrate Pnv-VP-U Folivane-Plus with Ascorbic Acid Precursors Abavite Children's Chewable Multi-vitamin TL-Fluorivite Tonimol Cap Liq Thiamine Tricare Prenatal Poly-Vitamin with Fluoride Avon Vitadvance Multi-kids Complete Multiple Vitamin Plus Minerals Tab One A Day Tab Vita Vim Multivitamins and Minerals Tab Se-Care Conceive Prenatal Formula Tab Multiple Vitamins and Minerals WesTab Plus Escavite Lq Cc II TriStart DHA Xyzbac G Multivitamins W Iron PR Natal 400 ec B-plus - Tab Prometa Liqui Vita Vita Plex Tab Beminal With C Fortis Cap Floradix Formula Liq Vitamin B-1 Thiamine HCl 100mg Betaxin Gesticare DHA Multivitamines Pour Enfants (chewable Tablets) Triveen-Duo DHA Hi Potency Multi Tab Multivitamin C.R.T. X Multivitamin & Mineral Powder Mix Childrens Chewable Vitamin Tab Formula D.S. Multi-phyto Capsules M.V.I. Pediatric Multiple Vitamins With Minerals Tablets Omniquin Formula Gm Materna-tab Mega-vim 75 With Beta-carotene - Tablets Pregnancy Multivitamin Distilpure Msm Vege 1 Daily Tab Stress B Capsules With Vitamin C Classic Swiss One 10 Multivitamin and Mineral Tab FolaGent DHA Multipack II Stress Formula Vit B With C Complex Twin Ultra Liquid Orange Flavor B-complex For-2 Prenatal Plus 24 Multivitamins + Minerals Lysamine Diet Supp Amp-tab Stressmates Fibrik Mvc 9+4 Inj Multivitamin with 0.25 mg Fluoride RE Prenatal Multivitamin with Iron Duet DHA Balanced Multiple Vitamins Plus Iron for Women Integra Plus Multi-Vit with Fluoride Chewable Multiple Vitamins Plus Extra C Multi II IV Vi Tab MultiVitamin with Fluoride Drops Se-Tan PLUS Balanced B-100 B-complex Vitamins Tab Dynam Ampoule Et Tablet Infantol Drops Stress Formula Tab Vitafol Caplet Vitafol Plus Gtf Support Caplet PrePLUS Pro Hers Vanilla B Complex With C 550mg Prenatal Mega Antioxidant Premium Prenatal Hill.vite Adult Infuvite Multiple Vitamins Flintstones Multiple Vitamins Tab Multra With Iron Surbex 500 Filmtab Multiple Vitamins W Iron Tab Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Hemarexin Tab Multiple Vitamins & Minerals Tablets Ventrixyl Fe Moms Choice Rx Zalvit Lexazin B 6 Plus Liqui B Complex Plus Multi Nt-OX Azesco Paire OB Plus DHA PNV Prenatal Plus Multivitamin Vita-B-75 Cap Vitranol Fe Vitamin B Complex Plus 300mg Vitamin C Croq-vit Pour Enfants Maximum Once A Day Vitafol-OB Plus DHA Prenatal Supplement Plus DHA B50 B Complex Tab B Complex 500 Tab Multi-vitamines Enfants Comprime Vasula Tab Infant Multivitamin Drops Mega Capsules One Tablet Daily Mens Formula Stress Formula B Virol L-Methyl PNV DHA Trinatal GT Vitaphil DHA Viva CT Prenatal Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Alkadrenergy Tablets Provida OB Dayavite HemeNatal OB Men's Multi Master Formula Vitamin B1 Tab 2mg USP Multi B Select-OB Plus DHA Prenatal Supplement Plus DHA Vitamin B1 100 mg Vasculine Junior Multi Vitamins - Regular Materna Maxi 10 Tab DuetDHA Complete Liqui Infant Vitamins Nutri-Tab OB plus DHA Zeldana Complete-RF Prenatal OB Complete 400 Dexatran Daily-Vite Neonatal DHA Nrg Plus Liq Revival 1 Tab Multi Vitamin Drops with Fluoride WesCap-C-DHA C-force Childrens Chew Multi Vitamin Tab Vital-D Rx Card-floe II Tab Re Ob 90 DHA Multi Vitamin with Fluoride L.C. Supplement Multivitamin with fluoride Multi Vite Liq Junior bioJET Lipotropic Ctr Palm Springs Multvit and Min Tab Meplex T 750 MI-Vite RX B-100 Caps Cavan Folate OB Prenatabs FA Vita-Pac Maxum Multi-vite Toni Com Liq Twin G.F. Powder Vita Balance 2000 B-100 Complex Tablets O-Cal FA multivitamin Prenatal Vi-min Mega 13 Multivitamin Formula PreGen DHA Venexa FE Allbee C 800 Tab Jenliva Prenatal Plus Multivitamin Plus DHA MiniCaps Nutra-Z L.G.I.T. Multiple Vitamins W Minerals Tab C. Vit-min Formula Complete Natal DHA Poly-Vite/Iron Oral Solution Pregvit Pediatric Infuvite Multiple Vitamins Lipo-B-C Tab Dialyvite 3000 High Potency Vitamin B Complex + C Tab M.V.I.-12 vitaMedMD One Rx Vitamin B Complex W C Tab Women's Biomultiple Vitamin and Mineral Supplement Select OB Multivitamins Vit B1 Ctr Srt 100mg B1 Tab 100mg Multiple Vitamins With Iron Vit-HA Multi Vitamin and Zinc Supplement Irospan 24/6 Prenatvite Plus CitraNatal 90 DHA Taron-C DHA Balanced B 125 Srt Chewable Multiple Vitamins Tab Prenatal Supplement - Tab B-complex-50 Tab Everyday Multiple Vitamins With Iron Children's Chewable Tab Bewon Elixir Vitasure Ziphex PNV Tabs 29-1 Derma-force Se-Natal Vita-Rx Diabetic Vitamin MultiVitamin with Fluoride Novel Vita Davimet with Iron Balanced B-50 Complex Children Choice Multivitamin W Iron Chew Tab Multi #2 Natalvirt Ca Renate B1 400mg Ctr Tab Tonicol Et A-D-C Ampoules/comprimes TriAdvance Extra P.N. Vitamin-mineral Drink Mix Kids Stuff With Iron Tablets Poly-Vi-Flor with Iron Ultimate OB DHA Multiple Vitamins and Minerals Tab Vitrexyl Multi Vitamin Drops with Fluoride with Iron Livita Children Vitamin B Complex Suppl VitaXyme Kaydia Patch Flintstones Multiple Vitamins Plus Iron VIL-Rx Relnate DHA Centratex Neo-vites & Minerals Tab Vitogen B Stress C600 Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Multiple Vitamin Tab Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Nephrocaps-QT Childrens Chewab Vitamin W Chel Minerals Tandem OB Mega Plex III - Pck Duet DHA Concept OB Foltabs Prenatal Children's Chewable With Iron Dalivit PNV Prenatal Vitamin Surbex-500 With Zinc Balanced B50 Complex Davimet with Fluoride PR Natal 430 Vasodyn Tab Synergistic Manganese Capsules Folika-NC Multivitamins W Minerals Extra Strength Thiamine Hydrochloride Spark Cap Mega Balance Prenatal Vitamins Plus Vinacal Neo-bex Injectable Vitazyme Multi Vitamin & Minerals One Daily Vitamin and Mineral Dietary Supplement Multiple Vitamins Plus Iron - Tab Prena1 Se-Natal 19 Replavite Chewable Multivitamins Multi Vitamin, Iron and Fluoride Cedevita Plus Vitamin Supplement Enrich Core Pack - Children Vitamin and Mineral Supplement VitaPhil Aide Prenatal Vitamin and Mineral Supplement Children's Vitamins W Iron Chewable Zoo Chews Multivitamins and Minerals for Young Men Stress Tab With Zinc, Copper and Vitamin E Complete Mega B Stress Formula B-comp + 500mg Vit C Tab Thiamine HCl Inj 100mg/ml Fusion Plus OB Complete DHA Pro His Mint Hemocyte Plus MultiVitamin Drops with Fluoride and Iron Total Living Concepts Formula One - Tab FloraFol Glyco Plus Ect Multivitamines Et Mineraux Junior Regulier Complex 5 - Pwr Body Rox Vitamin B-1 100 Mg Tablets Infa Drops Multivitamins Finazol Innersource Tab P.N.P. Vitamin Drink Super Vita-vim With Beta-carotene - Tab Multinate DHA Prenatal Vitamins and Minerals Tablets Inatal Advance Hyporyl - Tab Vitamin B Tablets Tricare Prenatal DHA One Rx Multivitamin Ferra Naka Plus Vitamins Multisol Century Complete RE Nata Enviroflex - Tab Harvest Of Values All B Complex Tab Supravite Stress Avec Vit E Revit Tab Vtb Vitamin and Mineral Supplement P.R.O. Complex Cavan Heme OB N.E.U. Complex Thrivite Rx Vyqua T.R.I. B-plex Src Gestamine Comprimes Pnv-OB-dha Quflora FE Chela Iron Plus C,b Complex INATAL Ultra Men's 50+ Ellis Tonic Multi-Vitamin RE Nata OB Vit B Complex Ctr Cyroplex Twin Opti Pwr Vitranol Livron Plus Tab Vitaday Junior Tab Prenate Star Virt-C DHA Super-pote Vitamin Supplement Thiamine HCl Injection - Liq 100mg/ml Se-Plete DHA Everyday Multiple Vitamins Multitabs Revitalize Multi-vitamin and Mineral Complex Stress Ctr Srt Vigo Multivitamins Drops/lozenge HemeNatal OB plus DHA Mvc B-50 Complex Tab Nutra Boost B Complex Plus C 300mg Tab B Totum 500 Permathene-12 - Caplet PreTAB Phytoplex B Liq Virt-Bal DHA Plus Vitafant Vitafol OB Caplet Vitamin B Complex + C 300mg Cap Extra Once A Day Multivit with Fluoride Vitamine 110 Liq Hylazinc Beminal Fortis Elx Children's Chew Multi & Min Tab Vitamines Pour Bebes Et Enfants Vitrexate FE Chewable Adult Multivitamins With Minerals Advanced B & T Formula B Plus C 300 mg PureVit DualFe Plus Swiss Total One Vitamin B Cpd W Vit C Tab Animal Shapes w/Iron Chewtabs Multi Plex I - Tab Complexe B 75mg Adult Formula 50+ Dexivite Nata Komplete Glyco-aide Tab Manganese 50mg Plus B1 & E Tab Multivitamins and Minerals for Women Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Usana Megavitamin Tablets - Tab Men's PROTECT IRON Liquid Vitaflex Dietary Suplement Vol-Care Rx One A Day Advance Adults Multi-kid Poly-Vi-Flor Formula Fm Vitamins & Minerals Tab Phosthenine Vitamines Et Fer (ampoules Buvable) Natalvirt 90dha Flintstones Multiple Vitamins Multi Vitamin Drops with Fluoride and Iron Vitamin B1 100mg Tablet Virt-Caps Forty Plus Vitamin Supplement Vimeral Tab B With C 500 Cap Formula O.C. Garfield Chewable Multivits Plus Iron Tab Multiple Vitamins Childrens Chewable MVC-Fluoride PNV Ferrous Fumarate Docusate Folic Acid Prenatrix Vitachrom Gc Chromease Tab ahoSAN NESTABS Prenatal Multi-vitamin/Mineral Supplement Am Caps Animal Shapes Children's Vitamins Chewable New Chapter's D'adamo 4 Your Type Multiple for Type O Omega-3 Rx Complete M.V.I. Paediatric Maintain Multiple Vitamin & Minerals One Daily VITES Ribotin-E Vena-Bal DHA B Plus C 300mg Timed Release Multi Vitamin Plus Iron Potassium Plus Vit B Complex Women's Change Formula Sibergin B - Cap PreferaOB Ultra Hr B C Antistress Cap Maxine Vitamin and Mineral Supplement Hemarexin Amp Multi 1000 Multi-Vitamin with Fluoride Multivitamines Plus Fer Pour Enfants (chewable Tablets) Supravite Stress Avec Vit E Et Fer Bev B-150 NataFort Appedrine Prenatal Multi Spectrum - Tablet Childrens Chewable Vitamins Foltabs Prenatal Plus DHA Folica-V Formula Pro-B Dia-vite Fortamines 10 Capsules Gemvites Jr Tab Chewable Multra Plex Vitamin B1 Dialyvite Supreme D Chew.multiple Vits.with Extra C for Children Essential B Tablets Phytopure Vita-amine Cap 100mg Daily Energy Brand B-complex Multiple Vitamins and Minerals Capsules Vitaplex Multi Pro Vitafol Fe Plus C-B Complex Vitamin B1 Tab 100mg Multivitamins and Minerals - Complete Chewable Children's Complete Multivitamins With Essential Minerals NataChew Quflora Pediatric Drops V & M Vitamin and Mineral Supplement Allbee With Vitamin C Cap Prena1 Plus Davimet-M Gynedyn Tab Maxi 6 Liq Nutri-Tab OB Super Pantoplex Edge OB B Complex W Vitamin C Fortis Cap Thiamine Hydrochloride Injection USP, 100mg/ml Paramettes Adults Chewable Multiple Vit Plus Iron for Children Stress B&c Tab Prenatal, DHA Thiamine HCL 100 mg Vitamin B Complex W C 300mg Tab TriphroCaps Supravite Stress Avec Vit E Cuivre Et Zinc Q.T. 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Complex For Kids Only Chewable Multivitamins Great Day/am Formula Tab Vitamin B Complex 100 Tab Natal PNV Swiss One Multi Vit & Chel Min Tab Complete One A Day Tab WesCaps Obstetrix EC Hi Potency B52 B Complex Tab Neonatal Plus Vitamin Floriva Plus Thiamine Hydrochloride Inj 100mg/ml Chela Potassium Plus OBTREX DHA Combo Pack Vinate AZ Grand Master Formula Tab Childrens Chewable Multiple Vitamins Mebolic Pregvit Folic 4 Time Release B 100 Compound - Tablet Multivitamins and Minerals for Men Poly-VI-sol Drops Focalgin 90 DHA Super B Compound W 500mg Vit C Liquid B Complex 50 Stress Tab With Iron and Vitamin E Prenatol-M Supravite 10ml Ampoule Mor-vites Tab Women's Formula Vitamin B Complex Plus C 300mg Timed Release PNV-First B6 Plus Tab Dialyvite with Zinc Geritol Liquid MultiVitamin, Iron and Fluoride Drops Chewable Multiple Vitamins for Children Ply Vi Sol Chewable Tab Bal-Care DHA O-Cal Prenatal Vitamin Multi Vitamins & Minerals NeuroBion B-100 Hi Potency B Vitamins Tab B Complex W C Forte Cap Central-vite 18 Essential Stress B Complex With C, E & Iron WesNatal DHA Complete Revit Multi-vitamins and Minerals Kids Stuff Tablets Multi-12/k1 Pediatric Luna Vitamin and Mineral Bar for Women Maltlevol 12 Liq Children's Chewable Multiple Vitamins - Tab Sopalamine/3b Tab Virt-Vite Plus Viva Kids - Tab Betaxin Liq 100mg/ml Mangadyn Envirocomplex Vitramyn Oncovite Provida DHA Biovita Thiamine HCl Tab 100mg Multiple Vitamins Super Daily No 2 Neomultivite Children Choice Multivit Chewable Tab Virt Nate Master Key Multi Vitamin Multi Mineral Formula 2 Cedevita Sugar-free Vitamin Supplement Natural Source Spectrum With Beta Carotene Prenara Reno Caps Methaver Children's Multivitamins With Iron Infuvite Adult One A Day Advance Fem hormaSAN forte Vitafer - Liq Vigem 12 Liquid Twin Ultra Liquid Fruit Punch Flavor Zavitrol Stress B Complex With C and E Tab Multi-vitamins PureFe Plus TL-Care DHA Tendera-OB One-A-day Advance Fem - Tablets CitraNatal DHA NovaMV Multivitamin Trinatal Ultra Chewable Multivitamins Plus Iron CompleteNate Chewable Neo-bex Vita-vim With Beta-carotene - Tab Iron, Vit & Min Supp Multi-vitamin Dietary Supplement Hormodausse Plus Calc Et D Tab Vitafol One Stress Vitamin B With C Complex Tablets Swiss One Timed Release Tab Natavite Folic-K Cda-21 Vitamins With Non-medicinal Probiotic Complex Tender Age Multi Vitamins THIAMINE HYDROCHLORIDE injection, solution Phytofortis + Calcium A-D Virt-Advance B Complex W Vit C W Non-med Yeast&liver Tab Super Stress Capsules Iberet 500 Vitamin B Compound W C Tab 500mg Swiss One Vp-heme Ob Opti-manganese + B1 + C Caplet For Kids Only Chewable Multivit. Plus Iron Cavan-EC SOD DHA Quflora Pediatric Stress Formula Multivitamin Tablets USP Duet DHA 400 Keylosa Amladex Z Bec Tab B Complex With C 300mg Tab Garfield Chewable Multivitamins Tab B Complex 25mg Vitamin Supplement Vitamin & Mineral Formula 1 Dietary Supplement PreNatal 19 Multi Enfants Tab Marnatal F Mega Vitaminerals Poly-Vi-Sol E.S.T. Complex Multivitamin with 1.0 mg Fluoride Corvite Vita-worth B-complex Tablets Vitamin B Complex 50 Concept DHA TRONVite Dermamed Nutrition for troubled skin Stress Tablets Cavan Folate DHA Kanga Sport Vitamins B & C Plus Minerals B Complex 50 Vitamin Cap Formula Hh Renal Caps Dialysis/Stress Vitamin Supplement B-1 Caps 500mg Children's Chewable Vit and Min Tab Stress B Complex With C, E and Iron Tab Vitaphil 90 DHA Leritone Junior Multi Vitamin and Mineral vitamin Choice OB DHA Vitafol Ultra SetonET-EC OB Complete Prenatal Nutra-clear Vitamin B-Complex Prenatvite Complete Swical-energy-2 Xyzbac Vitamine B1 100 Mg - Tablet Senior Multi One Virt-Tabs Fortaplex Inj Childrens Chewable Multivitamins B Complex 50+ Caplet Multivitamin & Minerals (iron Free) Gtf-vitamin-minerals & Pancreatin Tab Virt-Pn Corvita Children's Chewable Multi Vitamins Feminique W Iron and Calcium Tab Prenatal Vitamin and Mineral Supplement Tab Olympian Multi Vit Plus Minerals Tab Prefera OB plus DHA Q.T. #4 Vitamin and Mineral Dietary Supplement Multi-Vitamin With Fluoride Folika-T DaVITE Adeks Tablets Folica BE NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Viamon Ampoules Et Comprimes Vita B Complex Tab Sun-rype Vitaburst Mega Plex IV - Pck WestGel DHA Infuvite Pediatric Virt-Nate Vitamine Du Groupe B Plus Fer - Liq Ultra Enerforce Multivitamin & Multimineral B Stress C + Iron & Vite Paramettes Chewable Multivits With Iron Tab Reaphirm Plant Source DHA Vol-Tab Rx Revit Plus Cap Childrens Chewable Vitamins W Iron Multi-12 Pediatric Nutrilite Double X Trinatal Rx 1 B-plex THIAMINE HCl Biovim Tab Children's Chewable Multiple Vit.plus Iron Dialyvite Flinstones Multiple Plus Iron Folet DHA Multi Vitamines - Liq Folika-V Multi Rol Numark Multivitamins tensioSAN B50 Complex B-complex With Vitamin C, Biotin, Folic Acid Complete Multivitamins and Minerals Tablets Timed Release RenaPlex Multi Tabs PM Caps Vitamin B Complex Tab Nephron FA Kindervites Obstetrix DHA Combo Pack Tricare Prenatal DHA One With Folate vitaMedMD Rx Plus Children's Chewable Multi-vitamin Complete With Minerals Wellness Formula Paramettes Chewable Multivitamins Plus Iron Adeks - Dps Multiple Vitamins Tab NovaFerrum Multivitamin with Iron Pediatric Drops Children's Chewable Multiple Vitamins (chewable Tablets) Zintrexyl-C Glyco Lite Ect Multi-Vitamin Fluoride Drops Tricare Prenatal 2-part Daily Prenatal Vitamin System Neo Bex Elixir Trinaz Hi Potency B Complex W Chelated Minerals Stress Formula Multi-B Comp + 500mg Vit C Cap Stress Forte Plus Lipotropic Factors Kanga-kid Vitamins & Iron Cal M Tab Timed Release B-complex 100 Children's Chewable Multivitamin and Multimineral Vol-Nate High Potency Multivitamins & Minerals Caplets Vitrexyl plus Iron Stress Complex 600 Avec Vit E Cuivre Zinc M.V.I. 12 Timed Release B-complex 50 Tini-cal Ampoules Foliflex Xvite B Complex Tablets Active FE Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Vit B Complex Plus Vit C 550mg Chela-chromium 200 Hylavite Hypo Vites Tab PreNatal Vitamins Plus Multi Vite Liq Adult Original Bioscal Forte Multi-vitamin Supplement Capsules Poly Vi Flor Chewable Tab Balanced B-50 B-complex Vitamins, Timed Rele Polymine Avec Zinc Et Cuivre Complete Multivitamins and Minerals for Children Multi-force for Women Tab Premium Prenatal - Tablets Balanced B100 Beminal With C Fortis Pws Vyo Cylate - Pwr Chewable Multiple Vitamins Plus Iron Tab Prenatal Plus Vitamins Twin G.F. Powder Vanilla Flavor CitraNatal Assure Vita-vim - Tab PNV-Select Swical-energy 3e Age B-complex 100 Sopalamine/3b Plus C Iron Polysaccharides Folic Acid DHA Iron Folate Plus Stresstabs + Zinc-copper Thiamiject Injection - Liq Im IV 100mg/ml For Kids Only Chewable Multivitamins - Tab healthy mamaBE WELL ROUNDED BE WELL ROUNDED RenaPlex-D Beminal 500 Tab Children's Multivitamins Osteo-force RE FAC-x Protect Plus SO 60 MultiVitamin with Fluoride Chewable Elite OB Prenatal Multivitamin Doctor's Choice Brand for Men Multi 12 Injection Kanga-kid Multi-vitamin & Mineral Multiple Vitamins With Iron Tablets Neonatal19 Nutrol-B-complex Omnivex RayaVit B-complex Tab Sopalamine 3b Plus Strovite One Caplets Multi-force for Adults Tab Super Charged Energy Vitogen B Stress C Vit E Zinc & Cop Vitamin B Compound With Vitamin C Fortis Capsule Dtc Zoo Chews Plus Iron Neo Vites Tab Thiamine HCl Tab 25mg Formula Lf Bev 29 Tab NEONATAL Complete Lipovite Complexe B-75 Formula F L W Materna - Tab Prenatal Plus Iron Fortistress Tab Livita Adults PR Natal 400 Kimchi Vitamin chewable multivitamin Preplus One Per Day Vitamin and Mineral Dietary Supplement SetonET Supravite Bouteille 250ml C-Nate DHA Megavites Tab Active OB B-50 Complex Complex-75 Dexifol Flintstones W Extra C Tab Multi Vitamin-mineral Formula Poly-VI-flor Acti-MN + B1 + C Caplet Alertonic Supravite C 1000 Phytovim Cap Twin Ultra Liquid Grape Flavor Balanced B-100 Timed Release Childrens Multiple Vit and Min Chew Tab Vita Day Tab Zatean-Pn Swiss One Multivitamin and Mineral Caplet Vitamin B Compound Tab Alsimine W Vitamins A D Escavite Bugs Bunny Chew Multi Vit Plus Iron Milltrium Senior Vitamin and Mineral Supplement Stress B & C Caplet Children's Chewable Multivitamin Complete With Minerals Formula Gly Carbassist Tablets OB Complete Petite B Complex With C 300mg Soluvit N Surbex-500 With Iron Prenatal Vitamin and Mineral Supplement -tab B Compound 50mg Tab Kanga-B Vitamin B Group + C Super Stress Mega B Plus 1000mg Vit C Tab Childrens Chewable Multiple Vitamins Plus Fe H.W. Children's Chewable Multi Vit & Mineral Prim - Royal P.M.T. TM-Vite RX Efferlife Multivitamins and Minerals Prenatryl Tricare Prenatal Quick Dissolve Vitamin and Mineral Supplement - Liq Stress B Complex With C,e, Zinc and Copper Thiamine Hydrochloride Injection, USP Multivitamines Et Mineraux Hi Potency Stress B Tension With C Puralor Timed Release Vita-vim Srt Kanga-V Multivitamins & Minerals Vitamines Et Mineraux Enfants 970 Multivitamins and Minerals for Young Women Cavan Prenatal Multi-Vitamin Drops with Fluoride and Iron Multiple Vit Plus Iron Tab Prevital Tab Medi Msm (methyl Sulfonyl Methane) FolaMed DHA Poly-Vite Pediatric Oral Solution Vitamines Et Mineraux Synergistic Manganese Cap Somarexin and C 1000 Niva-Plus Vitamin B1 100mg Orange Flavored Crystal Chews Tab CitraNatal Rx Orti B Multivitamins for Children Diaplex Tricare Prenatal DHA One One-A-day Advance Men's Dialyvite 5000 DuetDHA Balanced Childrens Chewable Multivitamins W Iron Multivitamines M-Natal Plus D'pantothenic Acid-B1-B2 Tab Deriton Folitin-Z NephPlex Rx Vitamin B Complex Virt-PN Vitamin B Complex 100 Thiamine HCl 100mg W C 20mg B Vitamin Compound With B12 Thunas
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682