7PO4 | pdb_00007po4

Assembly intermediate of human mitochondrial ribosome large subunit (largely unfolded rRNA with MALSU1, L0R8F8 and ACP)


Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
E [auth F]SCOP2B SuperfamilyRibosomal protein L4 8080706 3001146 SCOP2B (2022-06-29)
I [auth K]SCOP2B SuperfamilyRibosomal protein L13 8100460 3001134 SCOP2B (2022-06-29)
J [auth L]SCOP2B Superfamily50S Ribosomal protein L14-like 8072072 3000433 SCOP2B (2022-06-29)
M [auth O]SCOP2B SuperfamilyProkaryotic ribosomal protein L17 8033689 3000995 SCOP2B (2022-06-29)
Z [auth 1]SCOP2B SuperfamilyZn-binding ribosomal proteins 8075050 3001320 SCOP2B (2022-06-29)
GA [auth 9]SCOP2B SuperfamilyMitochondrial ribosomal protein L27-like 8053893 3002240 SCOP2B (2022-06-29)
FB [auth za]SCOP2B SuperfamilyNucleotidyltransferase-like 8100396 3000129 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
C [auth D]Ribosomal_L2e7po4D1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: Ribosomal_L2ECOD (1.6)
C [auth D]Ribosomal_L2_Ce7po4D2 A: beta barrelsX: SH3H: SH3T: SH3F: Ribosomal_L2_CECOD (1.6)
D [auth E]Ribosomal_L3e7po4E1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: Ribosomal_L3ECOD (1.6)
E [auth F]Ribosomal_L4e7po4F1 A: a/b three-layered sandwichesX: Ribosomal protein L4 (From Topology)H: Ribosomal protein L4 (From Topology)T: Ribosomal protein L4F: Ribosomal_L4ECOD (1.6)
F [auth H]Ribosomal_L9_N_1e7po4H1 A: a+b two layersX: L9 N-domain-likeH: L9 N-domain-like (From Topology)T: L9 N-domain-likeF: Ribosomal_L9_N_1ECOD (1.6)
H [auth J]Ribosomal_L11e7po4J2 A: alpha arraysX: HTHH: HTHT: Ribosomal protein L11, C-terminal domainF: Ribosomal_L11ECOD (1.6)
H [auth J]Ribosomal_L11_Ne7po4J1 A: a+b two layersX: Ribosomal protein L11/L12e N-terminal domain-likeH: Ribosomal protein L11/L12e N-terminal domain (From Topology)T: Ribosomal protein L11/L12e N-terminal domainF: Ribosomal_L11_NECOD (1.6)
I [auth K]Ribosomal_L13e7po4K1 A: a/b three-layered sandwichesX: Ribosomal protein L13/L15p/L18e/L32eH: Ribosomal protein L13 and L16-A (From Topology)T: Ribosomal protein L13 and L16-AF: Ribosomal_L13ECOD (1.6)
J [auth L]Ribosomal_L14e7po4L1 A: beta barrelsX: Ribosomal protein L14-likeH: Ribosomal protein L14-related (From Topology)T: Ribosomal protein L14-relatedF: Ribosomal_L14ECOD (1.6)
K [auth M]Ribosomal_L27Ae7po4M1 A: a/b three-layered sandwichesX: Ribosomal protein L13/L15p/L18e/L32eH: Ribosomal proteins L15p and L18e (From Topology)T: Ribosomal proteins L15p and L18eF: Ribosomal_L27AECOD (1.6)
L [auth N]Ribosomal_L16e7po4N1 A: a+b complex topologyX: alpha/beta-Hammerhead/Barrel-sandwich hybridH: alpha/beta-Hammerhead/Barrel-sandwich hybridT: Ribosomal protein L10eF: Ribosomal_L16ECOD (1.6)
M [auth O]Ribosomal_L17e7po4O1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Prokaryotic ribosomal protein L17 (From Topology)T: Prokaryotic ribosomal protein L17F: Ribosomal_L17ECOD (1.6)
N [auth P]Ribosomal_L18pe7po4P1 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: Ribosomal_L18pECOD (1.6)
O [auth Q]Ribosomal_L19e7po4Q1 A: beta barrelsX: SH3H: SH3T: SH3F: Ribosomal_L19ECOD (1.6)
P [auth R]Ribosomal_L20e7po4R1 A: alpha arraysX: PABP domain-likeH: Ribosomal protein L20 (From Topology)T: Ribosomal protein L20F: Ribosomal_L20ECOD (1.6)
Q [auth S]Ribosomal_L21pe7po4S1 A: beta barrelsX: Ribosomal protein L21p (From Topology)H: Ribosomal protein L21p (From Topology)T: Ribosomal protein L21pF: Ribosomal_L21pECOD (1.6)
R [auth T]Ribosomal_L22e7po4T1 A: a+b two layersX: Enolase-N/ribosomal proteinH: Ribosomal protein L22 (From Topology)T: Ribosomal protein L22F: Ribosomal_L22ECOD (1.6)
S [auth U]Ribosomal_L23_2e7po4U1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal proteins S24e, L23 and L15e (From Topology)T: Ribosomal proteins S24e, L23 and L15eF: Ribosomal_L23_2ECOD (1.6)
T [auth V]ribosomal_L24_1e7po4V1 A: beta barrelsX: SH3H: SH3T: SH3F: ribosomal_L24_1ECOD (1.6)
U [auth W]Ribosomal_L27e7po4W1 A: a+b complex topologyX: alpha/beta-Hammerhead/Barrel-sandwich hybridH: alpha/beta-Hammerhead/Barrel-sandwich hybridT: Ribosomal L27 proteinF: Ribosomal_L27ECOD (1.6)
V [auth X]Ribosomal_L28_1e7po4X1 A: few secondary structure elementsX: Ribosomal protein bL28-related (From Homology)H: Ribosomal protein bL28-relatedT: Ribosomal protein L28F: Ribosomal_L28_1ECOD (1.6)
W [auth Y]MRP-L47e7po4Y1 A: alpha bundlesX: Long alpha-hairpinH: Ribosomal protein L29 (L29p) (From Topology)T: Ribosomal protein L29 (L29p)F: MRP-L47ECOD (1.6)
X [auth Z]Ribosomal_L30e7po4Z1 A: a+b two layersX: Ribosomal protein L30p/L7e (From Topology)H: Ribosomal protein L30p/L7e (From Topology)T: Ribosomal protein L30p/L7eF: Ribosomal_L30ECOD (1.6)
Y [auth 0]KOG4080e7po401 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: KOG4080ECOD (1.6)
Z [auth 1]Ribosomal_L33e7po411 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: Ribosomal_L33ECOD (1.6)
AA [auth 2]Ribosomal_L34e7po421 A: extended segmentsX: 50S ribosomal protein L34 (From Topology)H: 50S ribosomal protein L34 (From Topology)T: 50S ribosomal protein L34F: Ribosomal_L34ECOD (1.6)
BA [auth 3]Ribosomal_L35pe7po431 A: a+b two layersX: Ribosomal protein L35p (From Topology)H: Ribosomal protein L35p (From Topology)T: Ribosomal protein L35pF: Ribosomal_L35pECOD (1.6)
CA [auth 5]PDCD9e7po451 A: a/b three-layered sandwichesX: Restriction endonuclease-likeH: Restriction endonuclease-like (From Topology)T: Restriction endonuclease-likeF: PDCD9ECOD (1.6)
DA [auth 6]PBPe7po461 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: PEBP-likeF: PBPECOD (1.6)
EA [auth 7]TGSe7po472 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: TGSECOD (1.6)
EA [auth 7]tRNA_SADe7po471 A: a+b two layersX: LuxS, MPP, ThrRS/AlaRS common domainH: LuxS, MPP, ThrRS/AlaRS common domainT: ThrRS/AlaRS editing domainF: tRNA_SADECOD (1.6)
FA [auth 8]MRP-L28e7po481 A: extended segmentsX: Mitochondrial 54S ribosomal protein L28 (From Topology)H: Mitochondrial 54S ribosomal protein L28 (From Topology)T: Mitochondrial 54S ribosomal protein L28F: MRP-L28ECOD (1.6)
GA [auth 9]MRP-L27e7po491 A: extended segmentsX: Mitochondrial 54S ribosomal protein L27 (From Topology)H: Mitochondrial 54S ribosomal protein L27 (From Topology)T: Mitochondrial 54S ribosomal protein L27F: MRP-L27ECOD (1.6)
HA [auth a]MRP-S32e7po4a1 A: extended segmentsX: Mitoribosomal protein mL42 (From Topology)H: Mitoribosomal protein mL42 (From Topology)T: Mitoribosomal protein mL42F: MRP-S32ECOD (1.6)
IA [auth b]L51_S25_CI-B8e7po4b1 A: a+b three layersX: Thioredoxin-likeH: Thioredoxin-like (From Topology)T: Thioredoxin-likeF: L51_S25_CI-B8ECOD (1.6)
JA [auth c]Ribonucleas_3_3e7po4c2 A: alpha arraysX: RNase III catalytic domain-like (From Topology)H: RNase III catalytic domain-like (From Topology)T: RNase III catalytic domain-likeF: Ribonucleas_3_3ECOD (1.6)
JA [auth c]dsrme7po4c1 A: a+b two layersX: dsRBD-likeH: dsRNA-binding domain-like (From Topology)T: dsRNA-binding domain-likeF: dsrmECOD (1.6)
KA [auth d]Tim44e7po4d1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: Tim44ECOD (1.6)
LA [auth e]MRP-L46e7po4e1 A: a+b two layersX: beta-GraspH: Nudix (From Topology)T: NudixF: MRP-L46ECOD (1.6)
MA [auth f]Ribosomal_S10_2e7po4f1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal protein S10 (From Topology)T: Ribosomal protein S10F: Ribosomal_S10_2ECOD (1.6)
NA [auth g]Img2e7po4g1 A: a+b two layersX: Glucose permease domain IIB-likeH: eIF1-like (From Topology)T: eIF1-likeF: Img2ECOD (1.6)
OA [auth h]Ribosomal_L50e7po4h1 A: alpha bundlesX: ACP-likeH: Acyl-carrier protein (ACP) (From Topology)T: Acyl-carrier protein (ACP)F: Ribosomal_L50ECOD (1.6)
PA [auth i]MRP-L51e7po4i1 A: alpha bundlesX: Long alpha-hairpinH: Mitoribosomal protein mL51 (From Topology)T: Mitoribosomal protein mL51F: MRP-L51ECOD (1.6)
QA [auth j]EUF08791e7po4j1 A: extended segmentsX: Mitoribosomal protein mL52 (From Topology)H: Mitoribosomal protein mL52 (From Topology)T: Mitoribosomal protein mL52F: EUF08791ECOD (1.6)
RA [auth k]MRP_L53e7po4k1 A: a+b three layersX: Thioredoxin-likeH: Thioredoxin-like (From Topology)T: Thioredoxin-likeF: MRP_L53ECOD (1.6)
TA [auth m]Mitoc_L55e7po4m1 A: few secondary structure elementsX: Ribosomal protein L31p (From Topology)H: Ribosomal protein L31p (From Topology)T: Ribosomal protein L31pF: Mitoc_L55ECOD (1.6)
UA [auth o]MRP-63e7po4o1 A: extended segmentsX: Mitoribosomal protein mL63 (From Topology)H: Mitoribosomal protein mL63 (From Topology)T: Mitoribosomal protein mL63F: MRP-63ECOD (1.6)
VA [auth p]RF-1_Ne7po4p1 A: a+b two layersX: dsRBD-likeH: Peptidyl-tRNA hydrolase domain-like (From Topology)T: Peptidyl-tRNA hydrolase domain-likeF: RF-1_NECOD (1.6)
XA [auth r]Ribosomal_S18e7po4r1 A: alpha arraysX: HTHH: HTHT: tri-helicalF: Ribosomal_S18ECOD (1.6)
YA [auth s]PDCD9e7po4s1 A: a/b three-layered sandwichesX: Restriction endonuclease-likeH: Restriction endonuclease-like (From Topology)T: Restriction endonuclease-likeF: PDCD9ECOD (1.6)
AB [auth u]Ribosomal_L12_N_1e7po4u1 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
BB [auth v]Ribosomal_L12_N_1e7po4v1 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
CB [auth w]Ribosomal_L12_N_1e7po4w1 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
DB [auth x]Ribosomal_L12_N_1e7po4x1 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
EB [auth y]Ribosomal_L12_N_1e7po4y1 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
ZA [auth t]Ribosomal_L12_N_1e7po4t1 A: alpha duplicates or obligate multimersX: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)T: Ribosomal protein L7/12, oligomerisation (N-terminal) domainF: Ribosomal_L12_N_1ECOD (1.6)
FB [auth za]RsfSe7po4za1 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: RsfSECOD (1.6)
GB [auth zb]Complex1_LYRe7po4zb1 A: alpha bundlesX: LYR protein (From Topology)H: LYR protein (From Topology)T: LYR proteinF: Complex1_LYRECOD (1.6)
HB [auth zc]PP-bindinge7po4zc1 A: alpha bundlesX: ACP-likeH: Acyl-carrier protein (ACP) (From Topology)T: Acyl-carrier protein (ACP)F: PP-bindingECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF05047Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain (L51_S25_CI-B8)Mitochondrial ribosomal protein L51 / S25 / CI-B8 domainThe proteins in this family are located in the mitochondrion. The family includes ribosomal protein L51, and S25. This family also includes mitochondrial NADH-ubiquinone oxidoreductase B8 subunit (CI-B8) EC:1.6.5.3. It is not known whether all member ...The proteins in this family are located in the mitochondrion. The family includes ribosomal protein L51, and S25. This family also includes mitochondrial NADH-ubiquinone oxidoreductase B8 subunit (CI-B8) EC:1.6.5.3. It is not known whether all members of this family form part of the NADH-ubiquinone oxidoreductase and whether they are also all ribosomal proteins. Structurally related to thioredoxin-fold.
Domain
C [auth D]PF03947Ribosomal Proteins L2, C-terminal domain (Ribosomal_L2_C)Ribosomal Proteins L2, C-terminal domainDomain
C [auth D]PF04280Tim44-like domain (Tim44)Tim44-like domainTim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane [1]. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostati ...Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane [1]. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostatic interactions and by penetrating the polar head group region [1]. This family includes the C-terminal region of Tim44 that has been shown to form a stable proteolytic fragment in yeast. This region is also found in a set of smaller bacterial proteins. The molecular function of the bacterial members of this family is unknown but transport seems likely. The crystal structure of the C terminal of Tim44 has revealed a large hydrophobic pocket which might play an important role in interacting with the acyl chains of lipid molecules in the mitochondrial membrane [3].
Domain
C [auth D]PF00181Ribosomal Proteins L2, RNA binding domain (Ribosomal_L2)Ribosomal Proteins L2, RNA binding domainDomain
D [auth E]PF00297Ribosomal protein L3 (Ribosomal_L3)Ribosomal protein L3- Family
D [auth E]PF1178839S mitochondrial ribosomal protein L46 (MRP-L46)39S mitochondrial ribosomal protein L46- Family
E [auth F]PF00338Ribosomal protein S10p/S20e (Ribosomal_S10)Ribosomal protein S10p/S20eThis family includes small ribosomal subunit S10 from prokaryotes and S20 from eukaryotes. Domain
E [auth F]PF00573Ribosomal protein L4/L1 family (Ribosomal_L4)Ribosomal protein L4/L1 family- Family
F [auth H]PF01281Ribosomal protein L9, N-terminal domain (Ribosomal_L9_N)Ribosomal protein L9, N-terminal domainDomain
F [auth H]PF10501Ribosomal subunit 39S (Ribosomal_L50)Ribosomal subunit 39SThe 39S ribosomal protein appears to be a subunit of one of the larger mitochondrial 66S or 70S units [1]. Under conditions of ethanol-stress in rats the larger subunit is largely dissociated into its smaller components [2]. In E. coli, in the absenc ...The 39S ribosomal protein appears to be a subunit of one of the larger mitochondrial 66S or 70S units [1]. Under conditions of ethanol-stress in rats the larger subunit is largely dissociated into its smaller components [2]. In E. coli, in the absence of the enzyme pseudouridine synthase (RluD) synthase, there is an accumulation of 50S and 30S subunits and the appearance of abnormal particles (62S and 39S), with concomitant loss of 70S ribosomes [2].
Domain
G [auth I]PF10244Mitochondrial ribosomal subunit (MRP-L51)Mitochondrial ribosomal subunit- Family
G [auth I]PF00466Ribosomal protein L10 (Ribosomal_L10)Ribosomal protein L10- Family
H [auth J]PF03946Ribosomal protein L11, N-terminal domain (Ribosomal_L11_N)Ribosomal protein L11, N-terminal domainThe N-terminal domain of Ribosomal protein L11 adopts an alpha/beta fold and is followed by the RNA binding C-terminal domain. Domain
H [auth J]PF00298Ribosomal protein L11, RNA binding domain (Ribosomal_L11)Ribosomal protein L11, RNA binding domainDomain
H [auth J]PF18699Mitoribosomal protein mL52 (MRPL52)Mitoribosomal protein mL52- Family
I [auth K]PF1078039S ribosomal protein L53/MRP-L53 (MRP_L53)39S ribosomal protein L53/MRP-L53- Family
I [auth K]PF00572Ribosomal protein L13 (Ribosomal_L13)Ribosomal protein L13- Family
J [auth L]PF00238Ribosomal protein L14p/L23e (Ribosomal_L14)Ribosomal protein L14p/L23eDomain
J [auth L]PF08561Mitochondrial ribosomal protein L37 (Ribosomal_L37)Mitochondrial ribosomal protein L37- Family
L [auth N]PF00252Ribosomal protein L16p/L10e (Ribosomal_L16)Ribosomal protein L16p/L10eDomain
M [auth O]PF01196Ribosomal protein L17 (Ribosomal_L17)Ribosomal protein L17- Family
N [auth P]PF00861Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast (Ribosomal_L18p)Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast- Family
O [auth Q]PF01245Ribosomal protein L19 (Ribosomal_L19)Ribosomal protein L19- Family
P [auth R]PF01084Ribosomal protein S18 (Ribosomal_S18)Ribosomal protein S18- Family
P [auth R]PF00453Ribosomal protein L20 (Ribosomal_L20)Ribosomal protein L20- Family
Q [auth S]PF00829Ribosomal prokaryotic L21 protein (Ribosomal_L21p)Ribosomal prokaryotic L21 protein- Family
R [auth T]PF00237Ribosomal protein L22p/L17e (Ribosomal_L22)Ribosomal protein L22p/L17eThis family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes. Domain
R [auth T]PF16320Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)Ribosomal protein L7/L12 dimerisation domainThis is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1]. Domain
S [auth U]PF16320Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)Ribosomal protein L7/L12 dimerisation domainThis is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1]. Domain
S [auth U]PF00276Ribosomal protein L23 (Ribosomal_L23)Ribosomal protein L23- Family
T [auth V]PF16320Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)Ribosomal protein L7/L12 dimerisation domainThis is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1]. Domain
T [auth V]PF17136Ribosomal proteins 50S L24/mitochondrial 39S L24 (ribosomal_L24)Ribosomal proteins 50S L24/mitochondrial 39S L24- Family
T [auth V]PF00467KOW motif (KOW)KOW motif- Family
U [auth W]PF16320Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)Ribosomal protein L7/L12 dimerisation domainThis is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1]. Domain
V [auth X]PF16320Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)Ribosomal protein L7/L12 dimerisation domainThis is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1]. Domain
V [auth X]PF00830Ribosomal L28 family (Ribosomal_L28)Ribosomal L28 family- Family
W [auth Y]PF16320Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)Ribosomal protein L7/L12 dimerisation domainThis is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1]. Domain
W [auth Y]PF06984Mitochondrial 39-S ribosomal protein L47 (MRP-L47) (MRP-L47)Mitochondrial 39-S ribosomal protein L47 (MRP-L47)- Family
X [auth Z]PF00327Ribosomal protein L30p/L7e (Ribosomal_L30)Ribosomal protein L30p/L7eThis family includes prokaryotic L30 and eukaryotic L7. Domain
Y [auth 0]PF01783Ribosomal L32p protein family (Ribosomal_L32p)Ribosomal L32p protein family- Family
AA [auth 2]PF00468Ribosomal protein L34 (Ribosomal_L34)Ribosomal protein L34- Family
BA [auth 3]PF01632Ribosomal protein L35 (Ribosomal_L35p)Ribosomal protein L35- Family
CA [auth 5]PF07147Mitochondrial 28S ribosomal protein S30 (PDCD9) (PDCD9)Mitochondrial 28S ribosomal protein S30 (PDCD9)- Family
DA [auth 6]PF01161Phosphatidylethanolamine-binding protein (PBP)Phosphatidylethanolamine-binding proteinDomain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
16SrRNA---
tRNAVal---
C [auth D]39S ribosomal protein L2, mitochondrial
D [auth E]39S ribosomal protein L3, mitochondrial
E [auth F]39S ribosomal protein L4, mitochondrial
F [auth H]39S ribosomal protein L9, mitochondrial
G [auth I]39S ribosomal protein L10, mitochondrial
H [auth J]39S ribosomal protein L11, mitochondrial
I [auth K]39S ribosomal protein L13, mitochondrial
J [auth L]39S ribosomal protein L14, mitochondrial
K [auth M]39S ribosomal protein L15, mitochondrial
L [auth N]39S ribosomal protein L16, mitochondrial
M [auth O]39S ribosomal protein L17, mitochondrial
N [auth P]39S ribosomal protein L18, mitochondrial
O [auth Q]39S ribosomal protein L19, mitochondrial
P [auth R]39S ribosomal protein L20, mitochondrial
Q [auth S]39S ribosomal protein L21, mitochondrial
R [auth T]39S ribosomal protein L22, mitochondrial
S [auth U]39S ribosomal protein L23, mitochondrial
T [auth V]39S ribosomal protein L24, mitochondrial
U [auth W]39S ribosomal protein L27, mitochondrial
V [auth X]39S ribosomal protein L28, mitochondrial
W [auth Y]39S ribosomal protein L47, mitochondrial
X [auth Z]39S ribosomal protein L30, mitochondrial
Y [auth 0]39S ribosomal protein L32, mitochondrial
Z [auth 1]39S ribosomal protein L33, mitochondrial
AA [auth 2]39S ribosomal protein L34, mitochondrial
BA [auth 3]39S ribosomal protein L35, mitochondrial
CA [auth 5]39S ribosomal protein L37, mitochondrial
DA [auth 6]39S ribosomal protein L38, mitochondrial-
EA [auth 7]39S ribosomal protein L39, mitochondrial
FA [auth 8]39S ribosomal protein L40, mitochondrial
GA [auth 9]39S ribosomal protein L41, mitochondrial
HA [auth a]39S ribosomal protein L42, mitochondrial
IA [auth b]39S ribosomal protein L43, mitochondrial
JA [auth c]39S ribosomal protein L44, mitochondrial
KA [auth d]39S ribosomal protein L45, mitochondrial
LA [auth e]39S ribosomal protein L46, mitochondrial
MA [auth f]39S ribosomal protein L48, mitochondrial-
NA [auth g]39S ribosomal protein L49, mitochondrial
OA [auth h]39S ribosomal protein L50, mitochondrial-
PA [auth i]39S ribosomal protein L51, mitochondrial
QA [auth j]39S ribosomal protein L52, mitochondrial
RA [auth k]39S ribosomal protein L53, mitochondrial-
SA [auth l]39S ribosomal protein L54, mitochondrial
TA [auth m]39S ribosomal protein L55, mitochondrial
UA [auth o]Ribosomal protein 63, mitochondrial
VA [auth p]Peptidyl-tRNA hydrolase ICT1, mitochondrial
WA [auth q]Growth arrest and DNA damage-inducible proteins-interacting protein 1-
XA [auth r]39S ribosomal protein S18a, mitochondrial
YA [auth s]39S ribosomal protein S30, mitochondrial
39S ribosomal protein L12, mitochondrial
FB [auth za]Mitochondrial assembly of ribosomal large subunit protein 1
GB [auth zb]MIEF1 upstream open reading frame protein
HB [auth zc]Acyl carrier protein, mitochondrial

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
C [auth D]IPR022669Large ribosomal subunit protein uL2, C-terminalDomain
C [auth D]IPR014722Large ribosomal subunit protein uL2, domain 2Homologous Superfamily
C [auth D]IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
C [auth D]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
C [auth D]IPR022666Large ribosomal subunit protein uL2, RNA-binding domainDomain
C [auth D]IPR002171Large ribosomal subunit protein uL2Family
D [auth E]IPR019926Large ribosomal subunit protein uL3, conserved siteConserved Site
D [auth E]IPR019927Large ribosomal subunit protein uL3, bacterial/organelle-typeFamily
D [auth E]IPR009000Translation protein, beta-barrel domain superfamilyHomologous Superfamily
D [auth E]IPR000597Large ribosomal subunit protein uL3Family
E [auth F]IPR013005Large ribosomal subunit protein uL4-likeFamily
E [auth F]IPR002136Large ribosomal subunit protein uL4Family
E [auth F]IPR023574Large ribosomal subunit protein uL4 domain superfamilyHomologous Superfamily
F [auth H]IPR036935Large ribosomal subunit protein bL9, N-terminal domain superfamilyHomologous Superfamily
F [auth H]IPR020070Large ribosomal subunit protein bL9, N-terminalDomain
F [auth H]IPR054302Large ribosomal subunit protein bL9m, C-terminal domainDomain
F [auth H]IPR009027Large ribosomal subunit protein bL9/RNase H1, N-terminalHomologous Superfamily
F [auth H]IPR000244Large ribosomal subunit protein bL9Family
G [auth I]IPR043141Large ribosomal subunit protein uL10-like domain superfamilyHomologous Superfamily
G [auth I]IPR001790Large ribosomal subunit protein uL10Family
G [auth I]IPR047865Large ribosomal subunit protein uL10, bacterial typeFamily
H [auth J]IPR020783Large ribosomal subunit protein uL11, C-terminalDomain
H [auth J]IPR000911Ribosomal protein uL11Family
H [auth J]IPR006519Large ribosomal subunit protein uL11, bacterial-typeFamily
H [auth J]IPR020784Large ribosomal subunit protein uL11, N-terminalDomain
H [auth J]IPR036769Large ribosomal subunit protein uL11, C-terminal domain superfamilyHomologous Superfamily
H [auth J]IPR036796Large ribosomal subunit protein uL11, N-terminal domain superfamilyHomologous Superfamily
I [auth K]IPR023563Large ribosomal subunit protein uL13, conserved siteConserved Site
I [auth K]IPR005822Large ribosomal subunit protein uL13Family
I [auth K]IPR036899Large ribosomal subunit protein uL13 superfamilyHomologous Superfamily
I [auth K]IPR005823Large ribosomal subunit protein uL13, bacterial-typeFamily
J [auth L]IPR036853Large ribosomal subunit protein uL14 superfamilyHomologous Superfamily
J [auth L]IPR000218Large ribosomal subunit protein uL14Family
K [auth M]IPR005749Large ribosomal subunit protein uL15, bacterial-typeFamily
K [auth M]IPR021131Large ribosomal subunit protein uL15/eL18Domain
K [auth M]IPR030878Large ribosomal subunit protein uL15Family
K [auth M]IPR036227Large ribosomal subunit protein uL15/eL18 superfamilyHomologous Superfamily
L [auth N]IPR036920Large ribosomal subunit protein uL16 superfamilyHomologous Superfamily
L [auth N]IPR000114Large ribosomal subunit protein uL16, bacterial-typeFamily
L [auth N]IPR016180Large ribosomal subunit protein uL16 domainDomain
L [auth N]IPR047873Large ribosomal subunit protein uL16Family
M [auth O]IPR036373Large ribosomal subunit protein bL17 superfamilyHomologous Superfamily
M [auth O]IPR000456Large ribosomal subunit protein bL17Family
N [auth P]IPR005484Large ribosomal subunit protein uL18, bacterial/plantae/animaliaFamily
N [auth P]IPR036967Small ribosomal subunit protein uS11 superfamilyHomologous Superfamily
O [auth Q]IPR001857Large ribosomal subunit protein bL19Family
O [auth Q]IPR038657Large ribosomal subunit protein bL19 superfamilyHomologous Superfamily
O [auth Q]IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
P [auth R]IPR035566Ribosomal protein bL20, C-terminalHomologous Superfamily
P [auth R]IPR005813Large ribosomal subunit protein bL20Family
Q [auth S]IPR028909Large ribosomal subunit protein bL21-likeFamily
Q [auth S]IPR001787Large ribosomal subunit protein bL21Family
Q [auth S]IPR036164Large ribosomal subunit protein bL21-like superfamilyHomologous Superfamily
R [auth T]IPR047867Large ribosomal subunit protein uL22, bacterial/organelle-typeFamily
R [auth T]IPR036394Ribosomal protein uL22 superfamilyHomologous Superfamily
R [auth T]IPR001063Large ribosomal subunit protein uL22Family
S [auth U]IPR012678Ribosomal protein uL23/eL15/eS24 core domain superfamilyHomologous Superfamily
S [auth U]IPR012677Nucleotide-binding alpha-beta plait domain superfamilyHomologous Superfamily
S [auth U]IPR013025Large ribosomal subunit protein uL23-likeFamily
T [auth V]IPR014722Large ribosomal subunit protein uL2, domain 2Homologous Superfamily
T [auth V]IPR008991Translation protein SH3-like domain superfamilyHomologous Superfamily
T [auth V]IPR003256Large ribosomal subunit protein uL24Family
T [auth V]IPR041988Large ribosomal subunit protein uL24, KOW domainDomain
T [auth V]IPR005824KOWDomain
T [auth V]IPR005825Large ribosomal subunit protein uL24, conserved siteConserved Site
U [auth W]IPR001684Large ribosomal subunit protein bL27Family
V [auth X]IPR037147Large ribosomal subunit protein bL28 superfamilyHomologous Superfamily
V [auth X]IPR026569Large ribosomal subunit protein bL28Family
V [auth X]IPR034704Large ribosomal subunit protein bL28/bL31-like superfamilyHomologous Superfamily
W [auth Y]IPR038340MRP-L47 superfamily, mitochondrialHomologous Superfamily
W [auth Y]IPR010729Large ribosomal subunit protein uL29m, mitochondrialFamily
X [auth Z]IPR036919Large ribosomal subunit protein uL30, ferredoxin-like fold domain superfamilyHomologous Superfamily
X [auth Z]IPR005996Large ribosomal subunit protein uL30, bacterial-typeFamily
X [auth Z]IPR016082Large ribosomal subunit protein uL30-like, ferredoxin-like fold domainDomain
Y [auth 0]IPR002677Large ribosomal subunit protein bL32Family
Y [auth 0]IPR051991Mitochondrial ribosomal protein bL32Family
Y [auth 0]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
Z [auth 1]IPR052008Mitochondrial ribosomal protein bL33Family
Z [auth 1]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
Z [auth 1]IPR038584Large ribosomal subunit protein bL33 superfamilyHomologous Superfamily
Z [auth 1]IPR001705Large ribosomal subunit protein bL33Family
AA [auth 2]IPR000271Large ribosomal subunit protein bL34Family
BA [auth 3]IPR021137Large ribosomal subunit protein bL35-likeFamily
BA [auth 3]IPR019338Large ribosomal subunit protein bL35mFamily
BA [auth 3]IPR037229Large ribosomal subunit protein bL35 superfamilyHomologous Superfamily
CA [auth 5]IPR052482Mitochondrial large ribosomal subunit mL37Family
CA [auth 5]IPR010793Large ribosomal subunit protein mL37/mL65Family
DA [auth 6]IPR036610PEBP-like superfamilyHomologous Superfamily
DA [auth 6]IPR008914Phosphatidylethanolamine-binding proteinFamily
DA [auth 6]IPR035810Phosphatidylethanolamine-binding protein, eukaryoticFamily
EA [auth 7]IPR012676TGS-likeHomologous Superfamily
EA [auth 7]IPR018163Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamilyHomologous Superfamily
EA [auth 7]IPR050062Proline-tRNA synthetaseFamily
EA [auth 7]IPR004095TGSDomain
EA [auth 7]IPR012675Beta-grasp domain superfamilyHomologous Superfamily
FA [auth 8]IPR019192Large ribosomal subunit protein mL40Family
FA [auth 8]IPR039145Large ribosomal subunit protein mL40, metazoa/plantsFamily
GA [auth 9]IPR019189Large ribosomal subunit protein mL41Family
HA [auth a]IPR019346Large ribosomal subunit protein mL42Family
IA [auth b]IPR007741Ribosomal protein/NADH dehydrogenase domainDomain
IA [auth b]IPR036249Thioredoxin-like superfamilyHomologous Superfamily
IA [auth b]IPR039927Large ribosomal subunit protein mL43Family
JA [auth c]IPR036389Ribonuclease III, endonuclease domain superfamilyHomologous Superfamily
JA [auth c]IPR044444Large ribosomal subunit protein mL44, dsRNA binding domain, metazoaDomain
JA [auth c]IPR055189Large ribosomal subunit protein mL44, endonuclease domainDomain
JA [auth c]IPR014720Double-stranded RNA-binding domainDomain
KA [auth d]IPR032710NTF2-like domain superfamilyHomologous Superfamily
KA [auth d]IPR007379Tim44-like domainDomain
KA [auth d]IPR051975Mitochondrial Large Ribosomal Subunit mL45Family
LA [auth e]IPR015797NUDIX hydrolase-like domain superfamilyHomologous Superfamily
LA [auth e]IPR021757Large ribosomal subunit protein mL46, N-terminalDomain
LA [auth e]IPR040008Large ribosomal subunit protein mL46Family
LA [auth e]IPR033650Large ribosomal subunit protein mL46, NUDIX domainDomain
MA [auth f]IPR027486Small ribosomal subunit protein uS10 domainDomain
MA [auth f]IPR027487Large ribosomal subunit protein mL48Family
MA [auth f]IPR036838Small ribosomal subunit protein uS10 domain superfamilyHomologous Superfamily
NA [auth g]IPR007740Large ribosomal subunit protein mL49Family
OA [auth h]IPR018305Large ribosomal subunit protein mL50Family
PA [auth i]IPR019373Large ribosomal subunit protein mL51Family
QA [auth j]IPR034596Large ribosomal subunit protein mL52Family
RA [auth k]IPR019716Large ribosomal subunit protein mL53Family
RA [auth k]IPR052473Mitochondrial Large Ribosomal Subunit mL53Family
SA [auth l]IPR013870Large ribosomal subunit protein mL54Family
TA [auth m]IPR044884Large ribosomal subunit protein mL55 superfamilyHomologous Superfamily
TA [auth m]IPR018615Large ribosomal subunit protein mL55Family
UA [auth o]IPR016576Large ribosomal subunit protein mL63Family
VA [auth p]IPR052104Mitochondrial Release Factor mL62Family
VA [auth p]IPR000352Peptide chain release factor class IDomain
WA [auth q]IPR018472Large ribosomal subunit protein mL64Family
WA [auth q]IPR043035Large ribosomal subunit protein mL64 domain superfamilyHomologous Superfamily
XA [auth r]IPR001648Small ribosomal subunit protein bS18Family
XA [auth r]IPR036870Small ribosomal subunit protein bS18 superfamilyHomologous Superfamily
YA [auth s]IPR039982Large ribosomal subunit protein mL65Family
YA [auth s]IPR010793Large ribosomal subunit protein mL37/mL65Family
IPR013823Large ribosomal subunit protein bL12, C-terminalDomain
IPR008932Large ribosomal subunit protein bL12, oligomerizationDomain
IPR036235Large ribosomal subunit protein bL12, oligomerization domain superfamilyHomologous Superfamily
IPR014719Ribosomal protein bL12, C-terminal/adaptor protein ClpS-likeHomologous Superfamily
IPR000206Large ribosomal subunit protein bL12Family
FB [auth za]IPR043519Nucleotidyltransferase superfamilyHomologous Superfamily
FB [auth za]IPR004394Protein Iojap/ribosomal silencing factor RsfSFamily
GB [auth zb]IPR008011Complex 1 LYR protein domainDomain
GB [auth zb]IPR045300MIEF1-MP, LYR domainDomain
HB [auth zc]IPR006162Phosphopantetheine attachment sitePTM
HB [auth zc]IPR009081Phosphopantetheine binding ACP domainDomain
HB [auth zc]IPR036736ACP-like superfamilyHomologous Superfamily
HB [auth zc]IPR003231Acyl carrier proteinFamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
C [auth D]PharosQ5T653
D [auth E]PharosP09001
E [auth F]PharosQ9BYD3
F [auth H]PharosQ9BYD2
G [auth I]PharosQ7Z7H8
H [auth J]PharosQ9Y3B7
I [auth K]PharosQ9BYD1
J [auth L]PharosQ6P1L8
K [auth M]PharosQ9P015
L [auth N]PharosQ9NX20
M [auth O]PharosQ9NRX2
N [auth P]PharosQ9H0U6
O [auth Q]PharosP49406
P [auth R]PharosQ9BYC9
R [auth T]PharosQ9NWU5
S [auth U]PharosQ16540
T [auth V]PharosQ96A35
U [auth W]PharosQ9P0M9
V [auth X]PharosQ13084
W [auth Y]PharosQ9HD33
X [auth Z]PharosQ8TCC3
Y [auth 0]PharosQ9BYC8
Z [auth 1]PharosO75394
AA [auth 2]PharosQ9BQ48
BA [auth 3]PharosQ9NZE8
CA [auth 5]PharosQ9BZE1
EA [auth 7]PharosQ9NYK5
FA [auth 8]PharosQ9NQ50
GA [auth 9]PharosQ8IXM3
HA [auth a]PharosQ9Y6G3
IA [auth b]PharosQ8N983
JA [auth c]PharosQ9H9J2
KA [auth d]PharosQ9BRJ2
MA [auth f]PharosQ96GC5
NA [auth g]PharosQ13405
OA [auth h]PharosQ8N5N7
PA [auth i]PharosQ4U2R6
QA [auth j]PharosQ86TS9
SA [auth l]PharosQ6P161
TA [auth m]PharosQ7Z7F7
UA [auth o]PharosQ9BQC6
VA [auth p]PharosQ14197
WA [auth q]PharosQ8TAE8
XA [auth r]PharosQ9NVS2
YA [auth s]PharosQ9NP92
PharosP52815
FB [auth za]PharosQ96EH3
GB [auth zb]PharosL0R8F8
HB [auth zc]PharosO14561