The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...
The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
This entry represents a SAM-like domain found in fungal mitoribosome protein mS41. The mitochondrion-specific ribosomal protein mS41 family comprises proteins that are integral components of the mitochondrial ribosome, also known as the mitoribosome ...
This entry represents a SAM-like domain found in fungal mitoribosome protein mS41. The mitochondrion-specific ribosomal protein mS41 family comprises proteins that are integral components of the mitochondrial ribosome, also known as the mitoribosome. These proteins play a crucial role in the dedicated translation machinery that synthesizes mitochondrial genome-encoded proteins, which include essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are tethered to the mitochondrial inner membrane, ensuring that translation products are cotranslationally integrated into the membrane. Additionally, members of the mS41 family are implicated in the regulation of telomere length, a process essential for maintaining chromosome stability and cellular lifespan. Certain members are also required for survival upon exposure to specific environmental stressors, such as the K1 killer toxin.